Why Are There So Many Antihistamines, youtube mp3 indir
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Why Are There So Many Antihistamines? 🤧💊
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☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️
🔗 L I N K S 🔗
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📜 S O U R C E S 📜
Full annotated script available for free on Patreon: https://www.patreon.com/posts/antihistamines-102208961
Blockbuster Drugs: the Rise and Decline of the Pharmaceutical Industry by Jie Jack Li https://amzn.to/3U4WnuM (affiliate link)
Ten Drugs by Thomas Hager https://amzn.to/4cFkZSj (affiliate link)
Histamine pharmacology: from Sir Henry Dale to the 21st century (2020) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012941/
Histamine receptors and antihistamines: from discovery to clinical applications (2014) https://pubmed.ncbi.nlm.nih.gov/24925401/
Histamine and itch (2014) https://www.ncbi.nlm.nih.gov/books/NBK200934/
Frontiers in Clinical Drug Research - Anti-Allergy Agents (2018) https://www.google.com/books/edition/Frontiers_in_Clinical_Drug_Research_Anti/EIJoDwAAQBAJ?hl=en&gbpv=0
Allergy https://www.ncbi.nlm.nih.gov/books/NBK545237/
Allergic rhinitis https://www.nature.com/articles/s41572-020-00227-0
Inverse Agonism and Functional Selectivity (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165953/
Histamine H1 Receptor https://www.sciencedirect.com/topics/neuroscience/histamine-h1-receptor
Histamine and the antiallergic antihistamines: a history of their discoveries (1999) https://pubmed.ncbi.nlm.nih.gov/10444205/
Dale and Laidlaw isolate histamine (1910) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1512903/pdf/jphysiol02557-0034.pdf
Dale and Richards experiment with histamine (1911) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402694/pdf/jphysiol01757-0036.pdf
Halpern discovers Phenergan https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1591171/pdf/canmedaj00625-0017.pdf
The Claritin Effect; Prescription for Profit (2001) https://www.nytimes.com/2001/03/11/magazine/the-claritin-effect-prescription-for-profit.html
As Blockbuster Claritin Goes Generic, Schering-Plough Pushes a Close Sibling (2002) https://www.wsj.com/articles/SB1016748743581330920
💻 C O N T A C T 💻
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⌛T I M E S T A M P S ⌛
0:00 intro
0:34 The Discovery of Histamine
5:46 The First Antihistamines
12:33 The Rise of Non-Drowsy (Second Generation) H1 Antihistamines
19:34 Tagamet: the first blockbuster
#historyofmedicine #medicalhistory